Valorization of Lignocellulose by Producing Polyhydroxyalkanoates under Circular Bioeconomy Premises: Facts and Challenges

In light of the current concerns about environmental issues caused by excessive use fossil resources, more emphasis has been paid to transition a sustainable and circular economy. Bioplastics as eco-friendly products originating from biomass wastes have gained much attention solve problem plastic pollution. Among them, polyhydroxyalkanoates (PHAs) are microbial polyesters produced using various feedstocks─renewable or recycled waste materials─contributing commercial life cycle being part bioeconomy. However, scale-up PHA process cost effectively sustainably remains challenging for large-scale industrial applications. This perspective provides comprehensive overview insights into lignocellulosic biomass’s role in achieving Emerging greener conversion technologies discussed characterize energy demand, cost, sustainability within biorefinery production. addition, recent advances synthetic biology fermentation processes production discussed. Technological challenges, i.e., bioreactor setup, downstream operation, inconsistent properties improve PHAs help transfer this technology real-world applications, also addressed.